This paper describes the effect of polyomavirus T antigens on CBP/p300, and suggests that the T antigens use additional mechanisms in the transformation and immortalization of cells. Congratulations to Mayte Saenz-Robles and all the authors!
Ping An, Mayte Saenz-Robles and Jim Pipas have recently published a new review in Annual Reviews in Microbiology. The review discusses the amazing molecular machines of the T antigens of polyomaviruses. You can read the paper here.
Graduate students Nicole Seneca and Tushar Gupta will be giving a talk on their current research at the DNA Tumour Virus Meeting in Montreal, Canada on July 16 – 21st. Nicole’s talk is titled “The Variable Host Range Region of BK and JC Polyomavirus T-Antigens, But Not SV40 T-Antigen, Suppresses Transformation in MEFs” and Tushar’s talk is “Role of activator E2Fs in SV40 large T antigen mediated proliferation and transformation.”
Congratulations are in order! Zoe Cesarz and Christina Comunale, two of our undergraduate researchers in the lab, have been awarded a 2012 Howard Hughes Medical Institute Undergraduate Research Fellowship in the Department of Biological Sciences.
Welcome to the Pipas Lab website.